Malfunctioning of the Iron–Sulfur Cluster Assembly Machinery in Saccharomyces cerevisiae Produces Oxidative Stress via an Iron-Dependent Mechanism, Causing Dysfunction in Respiratory Complexes

Biogenesis and recycling of iron–sulfur (Fe–S) clusters play important roles in the iron homeostasis mechanisms involved in mitochondrial function. In Saccharomyces cerevisiae, the Fe–S clusters are assembled into apoproteins by the iron–sulfur cluster machinery (ISC). The aim of the present study w...

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Detalles Bibliográficos
Autores principales: Gomez, Mauricio, Pérez-Gallardo, Rocío V., Sánchez, Luis A., Díaz-Pérez, Alma L., Cortés-Rojo, Christian, Meza Carmen, Victor, Saavedra-Molina, Alfredo, Lara-Romero, Javier, Jiménez-Sandoval, Sergio, Rodríguez, Francisco, Rodríguez-Zavala, José S., Campos-García, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214746/
https://www.ncbi.nlm.nih.gov/pubmed/25356756
http://dx.doi.org/10.1371/journal.pone.0111585

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