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The ESAT-6 Protein of Mycobacterium tuberculosis Interacts with Beta-2-Microglobulin (β2M) Affecting Antigen Presentation Function of Macrophage
ESAT-6, an abundantly secreted protein of Mycobacterium tuberculosis (M. tuberculosis) is an important virulence factor, inactivation of which leads to reduced virulence of M. tuberculosis. ESAT-6 alone, or in complex with its chaperone CFP-10 (ESAT-6:CFP-10), is known to modulate host immune respon...
Autores principales: | Sreejit, Gopalkrishna, Ahmed, Asma, Parveen, Nazia, Jha, Vishwanath, Valluri, Vijaya Lakshmi, Ghosh, Sudip, Mukhopadhyay, Sangita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214792/ https://www.ncbi.nlm.nih.gov/pubmed/25356553 http://dx.doi.org/10.1371/journal.ppat.1004446 |
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