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Structural and functional characterization of salmon STAT1, STAT2 and IRF9 homologs sheds light on interferon signaling in teleosts

Mammalian IRF9 and STAT2, together with STAT1, form the ISGF3 transcription factor complex, which is critical for type I interferon (IFN)-induced signaling, while IFNγ stimulation is mediated by homodimeric STAT1 protein. Teleost fish are known to possess most JAK and STAT family members, however, d...

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Detalles Bibliográficos
Autores principales:	Sobhkhez, Mehrdad, Skjesol, Astrid, Thomassen, Ernst, Tollersrud, Linn Greiner, Iliev, Dimitar B., Sun, Baojian, Robertsen, Børre, Jørgensen, Jorunn B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215117/ https://www.ncbi.nlm.nih.gov/pubmed/25379383 http://dx.doi.org/10.1016/j.fob.2014.09.007

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