Setting Limits: Maintaining order in a large gene family

Odorant receptor (OR) gene choice is a paradigmatic example of stochastic regulation in which olfactory neurons choose one OR from > 1,000 possibilities. Recent biochemical, mathematical, and in vivo findings have revealed key players, introduced new axes of control, and brought the core mechanis...

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Detalles Bibliográficos
Autores principales: Abdus-Saboor, Ishmail, Fleischmann, Alexander, Shykind, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Point of View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215173/
https://www.ncbi.nlm.nih.gov/pubmed/25764336
http://dx.doi.org/10.4161/trns.28978
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author Abdus-Saboor, Ishmail
Fleischmann, Alexander
Shykind, Benjamin
author_facet Abdus-Saboor, Ishmail
Fleischmann, Alexander
Shykind, Benjamin
author_sort Abdus-Saboor, Ishmail
collection PubMed
description Odorant receptor (OR) gene choice is a paradigmatic example of stochastic regulation in which olfactory neurons choose one OR from > 1,000 possibilities. Recent biochemical, mathematical, and in vivo findings have revealed key players, introduced new axes of control, and brought the core mechanisms of the process into sharper focus.
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spelling pubmed-42151732015-09-27 Setting Limits: Maintaining order in a large gene family Abdus-Saboor, Ishmail Fleischmann, Alexander Shykind, Benjamin Transcription Point of View Odorant receptor (OR) gene choice is a paradigmatic example of stochastic regulation in which olfactory neurons choose one OR from > 1,000 possibilities. Recent biochemical, mathematical, and in vivo findings have revealed key players, introduced new axes of control, and brought the core mechanisms of the process into sharper focus. Landes Bioscience 2014-05-06 /pmc/articles/PMC4215173/ /pubmed/25764336 http://dx.doi.org/10.4161/trns.28978 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Point of View
Abdus-Saboor, Ishmail
Fleischmann, Alexander
Shykind, Benjamin
Setting Limits: Maintaining order in a large gene family
title Setting Limits: Maintaining order in a large gene family
title_full Setting Limits: Maintaining order in a large gene family
title_fullStr Setting Limits: Maintaining order in a large gene family
title_full_unstemmed Setting Limits: Maintaining order in a large gene family
title_short Setting Limits: Maintaining order in a large gene family
title_sort setting limits: maintaining order in a large gene family
topic Point of View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215173/
https://www.ncbi.nlm.nih.gov/pubmed/25764336
http://dx.doi.org/10.4161/trns.28978
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