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CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3′ processing

AAUAAA is the most highly conserved motif in eukaryotic mRNA polyadenylation sites and, in mammals, is specifically recognized by the multisubunit CPSF (cleavage and polyadenylation specificity factor) complex. Despite its critical functions in mRNA 3′ end formation, the molecular basis for CPSF–AAU...

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Detalles Bibliográficos
Autores principales:	Chan, Serena L., Huppertz, Ina, Yao, Chengguo, Weng, Lingjie, Moresco, James J., Yates, John R., Ule, Jernej, Manley, James L., Shi, Yongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215182/ https://www.ncbi.nlm.nih.gov/pubmed/25301780 http://dx.doi.org/10.1101/gad.250993.114

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