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New Insights about Enzyme Evolution from Large Scale Studies of Sequence and Structure Relationships
Understanding how enzymes have evolved offers clues about their structure-function relationships and mechanisms. Here, we describe evolution of functionally diverse enzyme superfamilies, each representing a large set of sequences that evolved from a common ancestor and that retain conserved features...
Autores principales: | Brown, Shoshana D., Babbitt, Patricia C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215206/ https://www.ncbi.nlm.nih.gov/pubmed/25210038 http://dx.doi.org/10.1074/jbc.R114.569350 |
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