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Postinduction serum infliximab trough level and decrease of C-reactive protein level are associated with durable sustained response to infliximab: a retrospective analysis of the ACCENT I trial
BACKGROUND: Serum infliximab trough levels correlate with efficacy; dose escalation is often beneficial in patients with Crohn's disease who stop responding to infliximab treatment. OBJECTIVE: To carry out a post hoc analysis of A Crohn's Disease Clinical Trial Evaluating Infliximab in a N...
Autores principales: | Cornillie, Freddy, Hanauer, Stephen B, Diamond, Robert H, Wang, Jianping, Tang, Kezhen L, Xu, Zhenhua, Rutgeerts, Paul, Vermeire, Séverine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215276/ https://www.ncbi.nlm.nih.gov/pubmed/24474383 http://dx.doi.org/10.1136/gutjnl-2012-304094 |
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