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Tendons – time to revisit inflammation
It is currently widely accepted among clinicians that chronic tendinopathy is caused by a degenerative process devoid of inflammation. Current treatment strategies are focused on physical treatments, peritendinous or intratendinous injections of blood or blood products and interruption of painful st...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215290/ https://www.ncbi.nlm.nih.gov/pubmed/23476034 http://dx.doi.org/10.1136/bjsports-2012-091957 |
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author | Rees, Jonathan D Stride, Matthew Scott, Alex |
author_facet | Rees, Jonathan D Stride, Matthew Scott, Alex |
author_sort | Rees, Jonathan D |
collection | PubMed |
description | It is currently widely accepted among clinicians that chronic tendinopathy is caused by a degenerative process devoid of inflammation. Current treatment strategies are focused on physical treatments, peritendinous or intratendinous injections of blood or blood products and interruption of painful stimuli. Results have been at best, moderately good and at worst a failure. The evidence for non-infammatory degenerative processes alone as the cause of tendinopathy is surprisingly weak. There is convincing evidence that the inflammatory response is a key component of chronic tendinopathy. Newer anti-inflammatory modalities may provide alternative potential opportunities in treating chronic tendinopathies and should be explored further. |
format | Online Article Text |
id | pubmed-4215290 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-42152902014-11-05 Tendons – time to revisit inflammation Rees, Jonathan D Stride, Matthew Scott, Alex Br J Sports Med Review It is currently widely accepted among clinicians that chronic tendinopathy is caused by a degenerative process devoid of inflammation. Current treatment strategies are focused on physical treatments, peritendinous or intratendinous injections of blood or blood products and interruption of painful stimuli. Results have been at best, moderately good and at worst a failure. The evidence for non-infammatory degenerative processes alone as the cause of tendinopathy is surprisingly weak. There is convincing evidence that the inflammatory response is a key component of chronic tendinopathy. Newer anti-inflammatory modalities may provide alternative potential opportunities in treating chronic tendinopathies and should be explored further. BMJ Publishing Group 2014-11 2013-03-09 /pmc/articles/PMC4215290/ /pubmed/23476034 http://dx.doi.org/10.1136/bjsports-2012-091957 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Review Rees, Jonathan D Stride, Matthew Scott, Alex Tendons – time to revisit inflammation |
title | Tendons – time to revisit inflammation |
title_full | Tendons – time to revisit inflammation |
title_fullStr | Tendons – time to revisit inflammation |
title_full_unstemmed | Tendons – time to revisit inflammation |
title_short | Tendons – time to revisit inflammation |
title_sort | tendons – time to revisit inflammation |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215290/ https://www.ncbi.nlm.nih.gov/pubmed/23476034 http://dx.doi.org/10.1136/bjsports-2012-091957 |
work_keys_str_mv | AT reesjonathand tendonstimetorevisitinflammation AT stridematthew tendonstimetorevisitinflammation AT scottalex tendonstimetorevisitinflammation |