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Female resistance to pneumonia identifies lung macrophage nitric oxide synthase-3 as a therapeutic target

To identify new approaches to enhance innate immunity to bacterial pneumonia, we investigated the natural experiment of gender differences in resistance to infections. Female and estrogen-treated male mice show greater resistance to pneumococcal pneumonia, seen as greater bacterial clearance, dimini...

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Detalles Bibliográficos
Autores principales:	Yang, Zhiping, Huang, Yuh-Chin T, Koziel, Henry, de Crom, Rini, Ruetten, Hartmut, Wohlfart, Paulus, Thomsen, Reimar W, Kahlert, Johnny A, Sørensen, Henrik Toft, Jozefowski, Szczepan, Colby, Amy, Kobzik, Lester
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Human Biology and Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215537/ https://www.ncbi.nlm.nih.gov/pubmed/25317947 http://dx.doi.org/10.7554/eLife.03711

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