Cargando…
The general anaesthetic etomidate inhibits the excitability of mouse thalamocortical relay neurons by modulating multiple modes of GABA(A) receptor-mediated inhibition
Modulation of thalamocortical (TC) relay neuron function has been implicated in the sedative and hypnotic effects of general anaesthetics. Inhibition of TC neurons is mediated predominantly by a combination of phasic and tonic inhibition, together with a recently described ‘spillover’ mode of inhibi...
Autores principales: | Herd, Murray B, Lambert, Jeremy J, Belelli, Delia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215602/ https://www.ncbi.nlm.nih.gov/pubmed/24773078 http://dx.doi.org/10.1111/ejn.12601 |
Ejemplares similares
-
Tonic GABAergic inhibition, via GABA(A) receptors containing αβƐ subunits, regulates excitability of ventral tegmental area dopamine neurons
por: Tossell, Kyoko, et al.
Publicado: (2021) -
Protein kinase C regulates tonic GABA(A) receptor-mediated inhibition in the hippocampus and thalamus
por: Bright, Damian P, et al.
Publicado: (2013) -
Non-neuronal, slow GABA signalling in the ventrobasal thalamus targets δ-subunit-containing GABA(A) receptors
por: Jiménez-González, Cristina, et al.
Publicado: (2011) -
GABA(A) receptors can initiate the formation of functional inhibitory GABAergic synapses
por: Fuchs, Celine, et al.
Publicado: (2013) -
Serotonin excites fast-spiking interneurons in the striatum
por: Blomeley, Craig P, et al.
Publicado: (2009)