Prognostic role of “prion-like propagation” in SOD1-linked familial ALS: an alternative view

“Prion-like propagation” has recently been proposed for disease spread in Cu/Zn superoxide dismutase 1 (SOD1)-linked familial amyotrophic lateral sclerosis (ALS). Pathological SOD1 conformers are presumed to propagate via cell-to-cell transmission. In this model, the risk-based kinetics of neuronal...

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Detalles Bibliográficos
Autores principales: Sugaya, Keizo, Nakano, Imaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215625/
https://www.ncbi.nlm.nih.gov/pubmed/25400549
http://dx.doi.org/10.3389/fncel.2014.00359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215625/
https://www.ncbi.nlm.nih.gov/pubmed/25400549
http://dx.doi.org/10.3389/fncel.2014.00359

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