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J-147 a Novel Hydrazide Lead Compound to Treat Neurodegeneration: CeeTox(™) Safety and Genotoxicity Analysis
J-147 is a broad spectrum neuroprotective phenyl hydrazide compound with significant neurotrophic properties related to the induction of brain-derived neurotrophic factor (BDNF). Because this molecule is pleiotropic, it may have substantial utility in the treatment of a wide range of neurodegenerati...
Autores principales: | Lapchak, Paul A., Bombien, Rene, Rajput, Padmesh S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215638/ https://www.ncbi.nlm.nih.gov/pubmed/25364619 http://dx.doi.org/10.4172/2155-9562.1000158 |
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