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Does tadalafil prevent erectile dysfunction in patients undergoing radiation therapy for prostate cancer?
A recently published paper addressed the interesting topic of prevention of erectile dysfunction (ED) with tadalafil, a phosphodiesterase-type 5 inhibitor (PDE5i) in patients undergoing radiation therapy for localized prostate cancer.1 Tadalafil 5 mg or placebo was administered once-daily for 24 wee...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215677/ https://www.ncbi.nlm.nih.gov/pubmed/24969064 http://dx.doi.org/10.4103/1008-682X.133324 |
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author | Incrocci, Luca |
author_facet | Incrocci, Luca |
author_sort | Incrocci, Luca |
collection | PubMed |
description | A recently published paper addressed the interesting topic of prevention of erectile dysfunction (ED) with tadalafil, a phosphodiesterase-type 5 inhibitor (PDE5i) in patients undergoing radiation therapy for localized prostate cancer.1 Tadalafil 5 mg or placebo was administered once-daily for 24 weeks in patients undergoing external-beam radiotherapy (EBRT) or brachytherapy (BT) for prostate cancer. This randomized trial did not show superior efficacy of the active drug compared with placebo 4–6 weeks after stopping the study drug. Furthermore, patients younger than 65 years did not respond significantly better than older patients. |
format | Online Article Text |
id | pubmed-4215677 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-42156772014-11-04 Does tadalafil prevent erectile dysfunction in patients undergoing radiation therapy for prostate cancer? Incrocci, Luca Asian J Androl Invited Research Highlight A recently published paper addressed the interesting topic of prevention of erectile dysfunction (ED) with tadalafil, a phosphodiesterase-type 5 inhibitor (PDE5i) in patients undergoing radiation therapy for localized prostate cancer.1 Tadalafil 5 mg or placebo was administered once-daily for 24 weeks in patients undergoing external-beam radiotherapy (EBRT) or brachytherapy (BT) for prostate cancer. This randomized trial did not show superior efficacy of the active drug compared with placebo 4–6 weeks after stopping the study drug. Furthermore, patients younger than 65 years did not respond significantly better than older patients. Medknow Publications & Media Pvt Ltd 2014 2014-06-20 /pmc/articles/PMC4215677/ /pubmed/24969064 http://dx.doi.org/10.4103/1008-682X.133324 Text en Copyright: © Asian Journal of Andrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Invited Research Highlight Incrocci, Luca Does tadalafil prevent erectile dysfunction in patients undergoing radiation therapy for prostate cancer? |
title | Does tadalafil prevent erectile dysfunction in patients undergoing radiation therapy for prostate cancer? |
title_full | Does tadalafil prevent erectile dysfunction in patients undergoing radiation therapy for prostate cancer? |
title_fullStr | Does tadalafil prevent erectile dysfunction in patients undergoing radiation therapy for prostate cancer? |
title_full_unstemmed | Does tadalafil prevent erectile dysfunction in patients undergoing radiation therapy for prostate cancer? |
title_short | Does tadalafil prevent erectile dysfunction in patients undergoing radiation therapy for prostate cancer? |
title_sort | does tadalafil prevent erectile dysfunction in patients undergoing radiation therapy for prostate cancer? |
topic | Invited Research Highlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215677/ https://www.ncbi.nlm.nih.gov/pubmed/24969064 http://dx.doi.org/10.4103/1008-682X.133324 |
work_keys_str_mv | AT incrocciluca doestadalafilpreventerectiledysfunctioninpatientsundergoingradiationtherapyforprostatecancer |