Development of a minimal saponin vaccine adjuvant based on QS-21

Adjuvants are materials added to vaccines to enhance the immunological response to an antigen. QS-21 is a natural product adjuvant under investigation in numerous vaccine clinical trials, but its use is constrained by scarcity, toxicity, instability, and an enigmatic molecular mechanism of action. H...

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Detalles Bibliográficos
Autores principales: Fernández-Tejada, Alberto, Chea, Eric K., George, Constantine, Pillarsetty, NagaVaraKishore, Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Lewis, Jason S., Tan, Derek S., Gin, David Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215704/
https://www.ncbi.nlm.nih.gov/pubmed/24950335
http://dx.doi.org/10.1038/nchem.1963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215704/
https://www.ncbi.nlm.nih.gov/pubmed/24950335
http://dx.doi.org/10.1038/nchem.1963

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