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GRAF1a is a brain-specific protein that promotes lipid droplet clustering and growth, and is enriched at lipid droplet junctions
Lipid droplets are found in all cell types. Normally present at low levels in the brain, they accumulate in tumours and are associated with neurodegenerative diseases. However, little is known about the mechanisms controlling their homeostasis in the brain. We found that GRAF1a, the longest GRAF1 is...
Autores principales: | Lucken-Ardjomande Häsler, Safa, Vallis, Yvonne, Jolin, Helen E., McKenzie, Andrew N., McMahon, Harvey T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215711/ https://www.ncbi.nlm.nih.gov/pubmed/25189622 http://dx.doi.org/10.1242/jcs.147694 |
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