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The ‘SAR Matrix’ method and its extensions for applications in medicinal chemistry and chemogenomics
We describe the ‘Structure-Activity Relationship (SAR) Matrix’ (SARM) methodology that is based upon a special two-step application of the matched molecular pair (MMP) formalism. The SARM method has originally been designed for the extraction, organization, and visualization of compound series and a...
Autores principales: | Gupta-Ostermann, Disha, Bajorath, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215758/ https://www.ncbi.nlm.nih.gov/pubmed/25383183 http://dx.doi.org/10.12688/f1000research.4185.2 |
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