Nuclear Export of Human Hepatitis B Virus Core Protein and Pregenomic RNA Depends on the Cellular NXF1-p15 Machinery

Hepatitis B virus (HBV) core protein (HBc) can shuttle between nucleus and cytoplasm. Cytoplasm-predominant HBc is clinically associated with severe liver inflammation. Previously, we found that HBc arginine-rich domain (ARD) can associate with a host factor NXF1 (TAP) by coimmunoprecipitation. It i...

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Detalles Bibliográficos
Autores principales: Yang, Ching-Chun, Huang, Er-Yi, Li, Hung-Cheng, Su, Pei-Yi, Shih, Chiaho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215830/
https://www.ncbi.nlm.nih.gov/pubmed/25360769
http://dx.doi.org/10.1371/journal.pone.0106683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215830/
https://www.ncbi.nlm.nih.gov/pubmed/25360769
http://dx.doi.org/10.1371/journal.pone.0106683

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