Mutational Analysis Gives Insight into Substrate Preferences of a Nucleotidyl Cyclase from Mycobacterium avium

Mutational, crystallographic and phylogenetic analysis of nucleotidyl cyclases have been used to understand how these enzymes discriminate between substrates. Ma1120, a class III adenylyl cyclase (AC) from Mycobacterium avium, was used as a model to study the amino acid residues that determine subst...

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Detalles Bibliográficos
Autores principales: Syed, Wajeed, Colaςo, Melwin, Misquith, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215837/
https://www.ncbi.nlm.nih.gov/pubmed/25360748
http://dx.doi.org/10.1371/journal.pone.0109358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215837/
https://www.ncbi.nlm.nih.gov/pubmed/25360748
http://dx.doi.org/10.1371/journal.pone.0109358

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