Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine

[Image: see text] Pseudomonas aeruginosa produces the peptide siderophore pyoverdine, which is used to acquire essential Fe(3+) ions from the environment. PvdQ, an Ntn hydrolase, is required for the biosynthesis of pyoverdine. PvdQ knockout strains are not infectious in model systems, suggesting tha...

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Detalles Bibliográficos
Autores principales: Wurst, Jacqueline M., Drake, Eric J., Theriault, Jimmy R., Jewett, Ivan T., VerPlank, Lynn, Perez, Jose R., Dandapani, Sivaraman, Palmer, Michelle, Moskowitz, Samuel M., Schreiber, Stuart L., Munoz, Benito, Gulick, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215858/
https://www.ncbi.nlm.nih.gov/pubmed/24824984
http://dx.doi.org/10.1021/cb5001586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215858/
https://www.ncbi.nlm.nih.gov/pubmed/24824984
http://dx.doi.org/10.1021/cb5001586

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