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Human Frataxin Activates Fe–S Cluster Biosynthesis by Facilitating Sulfur Transfer Chemistry

[Image: see text] Iron–sulfur clusters are ubiquitous protein cofactors with critical cellular functions. The mitochondrial Fe–S assembly complex, which consists of the cysteine desulfurase NFS1 and its accessory protein (ISD11), the Fe–S assembly protein (ISCU2), and frataxin (FXN), converts substr...

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Detalles Bibliográficos
Autores principales:	Bridwell-Rabb, Jennifer, Fox, Nicholas G., Tsai, Chi-Lin, Winn, Andrew M., Barondeau, David P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215901/ https://www.ncbi.nlm.nih.gov/pubmed/24971490 http://dx.doi.org/10.1021/bi500532e

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