Engineering a Light-Regulated GABA(A) Receptor for Optical Control of Neural Inhibition

[Image: see text] Optogenetics has become an emerging technique for neuroscience investigations owing to the great spatiotemporal precision and the target selectivity it provides. Here we extend the optogenetic strategy to GABA(A) receptors (GABA(A)Rs), the major mediators of inhibitory neurotransmi...

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Detalles Bibliográficos
Autores principales: Lin, Wan-Chen, Davenport, Christopher M., Mourot, Alexandre, Vytla, Devaiah, Smith, Caleb M., Medeiros, Kathryne A., Chambers, James J., Kramer, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215903/
https://www.ncbi.nlm.nih.gov/pubmed/24819442
http://dx.doi.org/10.1021/cb500167u

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