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In COS Cells Vpu Can Both Stabilize Tetherin Expression and Counteract Its Antiviral Activity

The interferon-inducible cellular protein tetherin (CD317/BST-2) inhibits the release of a broad range of enveloped viruses. The HIV-1 accessory protein Vpu enhances virus particle release by counteracting this host restriction factor. While the antagonism of human tetherin by Vpu has been associate...

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Detalles Bibliográficos
Autores principales:	Waheed, Abdul A., Kuruppu, Nishani D., Felton, Kathryn L., D’Souza, Darren, Freed, Eric O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216104/ https://www.ncbi.nlm.nih.gov/pubmed/25360760 http://dx.doi.org/10.1371/journal.pone.0111628

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