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Optogenetic Measurement of Presynaptic Calcium Transients Using Conditional Genetically Encoded Calcium Indicator Expression in Dopaminergic Neurons
Calcium triggers dopamine release from presynaptic terminals of midbrain dopaminergic (mDA) neurons in the striatum. However, calcium transients within mDA axons and axon terminals are difficult to study and little is known about how they are regulated. Here we use a newly-developed method to measur...
Autores principales: | Sgobio, Carmelo, Kupferschmidt, David A., Cui, Guohong, Sun, Lixin, Li, Zheng, Cai, Huaibin, Lovinger, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216119/ https://www.ncbi.nlm.nih.gov/pubmed/25360513 http://dx.doi.org/10.1371/journal.pone.0111749 |
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