Cargando…

Analysis of the Influence of Cell Heterogeneity on Nanoparticle Dose Response

[Image: see text] Understanding the effect of variability in the interaction of individual cells with nanoparticles on the overall response of the cell population to a nanoagent is a fundamental challenge in bionanotechnology. Here, we show that the technique of time-resolved, high-throughput micros...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ware, Matthew J., Godin, Biana, Singh, Neenu, Majithia, Ravish, Shamsudeen, Sabeel, Serda, Rita E., Meissner, Kenith E., Rees, Paul, Summers, Huw D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216222/ https://www.ncbi.nlm.nih.gov/pubmed/24923782 http://dx.doi.org/10.1021/nn502356f

Ejemplares similares

Mechanism of Generation of ZnO Microstructures by Microwave-Assisted Hydrothermal Approach
por: Majithia, Ravish, et al.
Publicado: (2013)

A New Imaging Platform for Visualizing Biological Effects of Non-Invasive Radiofrequency Electric-Field Cancer Hyperthermia
por: Corr, Stuart J., et al.
Publicado: (2015)

The origin of heterogeneous nanoparticle uptake by cells
por: Rees, Paul, et al.
Publicado: (2019)

Mitigation of Quantum Dot Cytotoxicity by Microencapsulation
por: Romoser, Amelia, et al.
Publicado: (2011)

Radiofrequency treatment alters cancer cell phenotype
por: Ware, Matthew J., et al.
Publicado: (2015)

Quantification of Nanoparticle Dose and Vesicular Inheritance in Proliferating Cells
por: Summers, Huw D., et al.
Publicado: (2013)

Influence of Critical Parameters on Cytotoxicity Induced by Mesoporous Silica Nanoparticles
por: Ahmadi, Amirsadra, et al.
Publicado: (2022)

Increased Soluble CrkL in Serum of Breast Cancer Patients Is Associated with Advanced Disease
por: Srinivasan, Srimeenakshi, et al.
Publicado: (2019)

Encapsulation of FITC to monitor extracellular pH: a step towards the development of red blood cells as circulating blood analyte biosensors
por: Ritter, Sarah C., et al.
Publicado: (2011)

Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T(1) contrast
por: Ananta, Jeyarama S., et al.
Publicado: (2010)

Microwave-assisted synthesis of layered basic zinc acetate nanosheets and their thermal decomposition into nanocrystalline ZnO
por: Tarat, Afshin, et al.
Publicado: (2014)

Modeling of Nanotherapy Response as a Function of the Tumor Microenvironment: Focus on Liver Metastasis
por: Frieboes, Hermann B., et al.
Publicado: (2020)

Macrophage Polarization Contributes to the Anti-Tumoral Efficacy of Mesoporous Nanovectors Loaded with Albumin-Bound Paclitaxel
por: Leonard, Fransisca, et al.
Publicado: (2017)

Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION)
por: Singh, Neenu, et al.
Publicado: (2010)

Intravital microscopy for evaluating tumor perfusion of nanoparticles exposed to non-invasive radiofrequency electric fields
por: Lapin, Norman A., et al.
Publicado: (2016)

Pancreatic adenocarcinoma response to chemotherapy enhanced with non-invasive radio frequency evaluated via an integrated experimental/computational approach
por: Ware, Matthew J., et al.
Publicado: (2017)

Design and In Vitro Evaluation of Layer by Layer siRNA Nanovectors Targeting Breast Tumor Initiating Cells
por: Jaganathan, Hamsa, et al.
Publicado: (2014)

Automated Cell Identification and Tracking Using Nanoparticle Moving-Light-Displays
por: Tonkin, James A., et al.
Publicado: (2012)

Data-Driven Modeling of the Cellular Pharmacokinetics of Degradable Chitosan-Based Nanoparticles
por: Summers, Huw D., et al.
Publicado: (2021)

Spatial statistics is a comprehensive tool for quantifying cell neighbor relationships and biological processes via tissue image analysis
por: Summers, Huw D., et al.
Publicado: (2022)

Endolysosomal Mesoporous Silica Nanoparticle Trafficking along Microtubular Highways
por: Noureddine, Achraf, et al.
Publicado: (2021)

Determining jumping performance from a single body-worn accelerometer using machine learning
por: White, Mark G. E., et al.
Publicado: (2022)

Specific Tumor Localization of Immunogenic Lipid-Coated Mesoporous Silica Nanoparticles following Intraperitoneal Administration in a Mouse Model of Serous Epithelial Ovarian Cancer
por: Noureddine, Achraf, et al.
Publicado: (2023)

Direct Transfer of Mesoporous Silica Nanoparticles between Macrophages and Cancer Cells
por: Franco, Stefan, et al.
Publicado: (2020)

The Proteolytic Landscape of Ovarian Cancer: Applications in Nanomedicine
por: O’Connell, Cailin, et al.
Publicado: (2022)

Diffusion Mapping of Eosinophil‐Activation State
por: Piasecka, Justyna, et al.
Publicado: (2019)

Empirical comparison of genotoxic potency estimations: the in vitro DNA-damage ToxTracker endpoints versus the in vivo micronucleus assay
por: Wills, John W, et al.
Publicado: (2021)

Characterization of Free and Porous Silicon-Encapsulated Superparamagnetic Iron Oxide Nanoparticles as Platforms for the Development of Theranostic Vaccines
por: Lundquist, Charles M., et al.
Publicado: (2014)

Poisson‐event‐based analysis of cell proliferation
por: Summers, Huw D., et al.
Publicado: (2015)

Particle platforms for cancer immunotherapy
por: Serda, Rita Elena
Publicado: (2013)

Internalization of Red Blood Cell-Mimicking Hydrogel Capsules with pH-Triggered Shape Responses
por: Kozlovskaya, Veronika, et al.
Publicado: (2014)

Three-Dimensional In Vitro Co-Culture Model of Breast Tumor using Magnetic Levitation
por: Jaganathan, Hamsa, et al.
Publicado: (2014)

Heterogeneous Trimetallic Nanoparticles as Catalysts
por: Crawley, James W. M., et al.
Publicado: (2022)

Uterus-targeted liposomes for preterm labor management: studies in pregnant mice
por: Refuerzo, Jerrie S., et al.
Publicado: (2016)

Erectile Dysfunction in Behcet's Disease
por: Kaul, Neenu, et al.
Publicado: (2017)

Heterogeneous Kinetics in the Functionalization of Single Plasmonic Nanoparticles
por: Horáček, Matěj, et al.
Publicado: (2017)

Practical machine learning for disease diagnosis
por: Summers, Huw D.
Publicado: (2021)

Sex-dependent improvement in traumatic brain injury outcomes after liposomal delivery of dexamethasone in mice
por: Baudo, Gherardo, et al.
Publicado: (2023)

Activity Mapping of Children in Play Using Multivariate Analysis of Movement Events
por: ROCHA, JOANA N., et al.
Publicado: (2020)

Inhibition of human APE1 and MTH1 DNA repair proteins by dextran-coated γ-Fe(2)O(3) ultrasmall superparamagnetic iron oxide nanoparticles
por: Coskun, Erdem, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lmvtmb99qe7hesoo2ijnqlju59