Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine

A patient with Candida spondylitis failed two weeks of fluconazole combined with caspofungin, and the infection relapsed despite six weeks of liposomal amphotericin B followed by two months of fluconazole. Six months therapy with high dose liposomal amphotericin B combined with flucytosine effective...

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Autores principales: Storm, Line, Lausch, Karen R., Arendrup, Maiken C., Mortensen, Klaus L., Petersen, Eskild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216330/
https://www.ncbi.nlm.nih.gov/pubmed/25379389
http://dx.doi.org/10.1016/j.mmcr.2014.07.001
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author Storm, Line
Lausch, Karen R.
Arendrup, Maiken C.
Mortensen, Klaus L.
Petersen, Eskild
author_facet Storm, Line
Lausch, Karen R.
Arendrup, Maiken C.
Mortensen, Klaus L.
Petersen, Eskild
author_sort Storm, Line
collection PubMed
description A patient with Candida spondylitis failed two weeks of fluconazole combined with caspofungin, and the infection relapsed despite six weeks of liposomal amphotericin B followed by two months of fluconazole. Six months therapy with high dose liposomal amphotericin B combined with flucytosine effectively cured the patient.
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spelling pubmed-42163302014-11-06 Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine Storm, Line Lausch, Karen R. Arendrup, Maiken C. Mortensen, Klaus L. Petersen, Eskild Med Mycol Case Rep Article A patient with Candida spondylitis failed two weeks of fluconazole combined with caspofungin, and the infection relapsed despite six weeks of liposomal amphotericin B followed by two months of fluconazole. Six months therapy with high dose liposomal amphotericin B combined with flucytosine effectively cured the patient. Elsevier 2014-07-08 /pmc/articles/PMC4216330/ /pubmed/25379389 http://dx.doi.org/10.1016/j.mmcr.2014.07.001 Text en © 2014 International Society for Human and Animal Mycology http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Storm, Line
Lausch, Karen R.
Arendrup, Maiken C.
Mortensen, Klaus L.
Petersen, Eskild
Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine
title Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine
title_full Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine
title_fullStr Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine
title_full_unstemmed Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine
title_short Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine
title_sort vertebral infection with candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin b and flucytosine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216330/
https://www.ncbi.nlm.nih.gov/pubmed/25379389
http://dx.doi.org/10.1016/j.mmcr.2014.07.001
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