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Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy
Mucormycosis is a severe fungal infection that largely affects immunocompromised individuals. It carries a high morbidity and mortality rate and is characterised by extensive angioinvasion and necrosis of host tissue. This case report details success in treating disseminated mucormycosis in a paedia...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216331/ https://www.ncbi.nlm.nih.gov/pubmed/25379392 http://dx.doi.org/10.1016/j.mmcr.2014.08.002 |
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author | Campbell, Anita Cooper, Celia Davis, Stephen |
author_facet | Campbell, Anita Cooper, Celia Davis, Stephen |
author_sort | Campbell, Anita |
collection | PubMed |
description | Mucormycosis is a severe fungal infection that largely affects immunocompromised individuals. It carries a high morbidity and mortality rate and is characterised by extensive angioinvasion and necrosis of host tissue. This case report details success in treating disseminated mucormycosis in a paediatric patient with an underlying haematological malignancy. Treatment included institution of combination antifungal therapy with liposomal amphotericin B and caspofungin, aggressive surgical debridement of infected tissue and reversal of underlying immunosuppression. |
format | Online Article Text |
id | pubmed-4216331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-42163312014-11-06 Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy Campbell, Anita Cooper, Celia Davis, Stephen Med Mycol Case Rep Article Mucormycosis is a severe fungal infection that largely affects immunocompromised individuals. It carries a high morbidity and mortality rate and is characterised by extensive angioinvasion and necrosis of host tissue. This case report details success in treating disseminated mucormycosis in a paediatric patient with an underlying haematological malignancy. Treatment included institution of combination antifungal therapy with liposomal amphotericin B and caspofungin, aggressive surgical debridement of infected tissue and reversal of underlying immunosuppression. Elsevier 2014-08-11 /pmc/articles/PMC4216331/ /pubmed/25379392 http://dx.doi.org/10.1016/j.mmcr.2014.08.002 Text en © 2014 International Society for Human and Animal Mycology http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
spellingShingle | Article Campbell, Anita Cooper, Celia Davis, Stephen Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy |
title | Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy |
title_full | Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy |
title_fullStr | Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy |
title_full_unstemmed | Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy |
title_short | Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy |
title_sort | disseminated mucormycosis in a paediatric patient: lichthemia corymbifera successfully treated with combination antifungal therapy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216331/ https://www.ncbi.nlm.nih.gov/pubmed/25379392 http://dx.doi.org/10.1016/j.mmcr.2014.08.002 |
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