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Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy

Mucormycosis is a severe fungal infection that largely affects immunocompromised individuals. It carries a high morbidity and mortality rate and is characterised by extensive angioinvasion and necrosis of host tissue. This case report details success in treating disseminated mucormycosis in a paedia...

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Detalles Bibliográficos
Autores principales: Campbell, Anita, Cooper, Celia, Davis, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216331/
https://www.ncbi.nlm.nih.gov/pubmed/25379392
http://dx.doi.org/10.1016/j.mmcr.2014.08.002
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author Campbell, Anita
Cooper, Celia
Davis, Stephen
author_facet Campbell, Anita
Cooper, Celia
Davis, Stephen
author_sort Campbell, Anita
collection PubMed
description Mucormycosis is a severe fungal infection that largely affects immunocompromised individuals. It carries a high morbidity and mortality rate and is characterised by extensive angioinvasion and necrosis of host tissue. This case report details success in treating disseminated mucormycosis in a paediatric patient with an underlying haematological malignancy. Treatment included institution of combination antifungal therapy with liposomal amphotericin B and caspofungin, aggressive surgical debridement of infected tissue and reversal of underlying immunosuppression.
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spelling pubmed-42163312014-11-06 Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy Campbell, Anita Cooper, Celia Davis, Stephen Med Mycol Case Rep Article Mucormycosis is a severe fungal infection that largely affects immunocompromised individuals. It carries a high morbidity and mortality rate and is characterised by extensive angioinvasion and necrosis of host tissue. This case report details success in treating disseminated mucormycosis in a paediatric patient with an underlying haematological malignancy. Treatment included institution of combination antifungal therapy with liposomal amphotericin B and caspofungin, aggressive surgical debridement of infected tissue and reversal of underlying immunosuppression. Elsevier 2014-08-11 /pmc/articles/PMC4216331/ /pubmed/25379392 http://dx.doi.org/10.1016/j.mmcr.2014.08.002 Text en © 2014 International Society for Human and Animal Mycology http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Article
Campbell, Anita
Cooper, Celia
Davis, Stephen
Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy
title Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy
title_full Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy
title_fullStr Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy
title_full_unstemmed Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy
title_short Disseminated mucormycosis in a paediatric patient: Lichthemia corymbifera successfully treated with combination antifungal therapy
title_sort disseminated mucormycosis in a paediatric patient: lichthemia corymbifera successfully treated with combination antifungal therapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216331/
https://www.ncbi.nlm.nih.gov/pubmed/25379392
http://dx.doi.org/10.1016/j.mmcr.2014.08.002
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