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Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo

The elaboration of anterior–posterior (A–P) pattern is one of the earliest events during development and requires the precisely coordinated action of several players at the level of molecules, cells and tissues. In mammals, it is controlled by a specialized population of migratory extraembryonic epi...

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Detalles Bibliográficos
Autores principales: Stower, Matthew J., Srinivas, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216468/
https://www.ncbi.nlm.nih.gov/pubmed/25349454
http://dx.doi.org/10.1098/rstb.2013.0546
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author Stower, Matthew J.
Srinivas, Shankar
author_facet Stower, Matthew J.
Srinivas, Shankar
author_sort Stower, Matthew J.
collection PubMed
description The elaboration of anterior–posterior (A–P) pattern is one of the earliest events during development and requires the precisely coordinated action of several players at the level of molecules, cells and tissues. In mammals, it is controlled by a specialized population of migratory extraembryonic epithelial cells, the anterior visceral endoderm (AVE). The AVE is a signalling centre that is responsible for several important patterning events during early development, including specifying the orientation of the A–P axis and the position of the heart with respect to the brain. AVE cells undergo a characteristic stereotypical migration which is crucial to their functions.
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spelling pubmed-42164682014-12-05 Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo Stower, Matthew J. Srinivas, Shankar Philos Trans R Soc Lond B Biol Sci Articles The elaboration of anterior–posterior (A–P) pattern is one of the earliest events during development and requires the precisely coordinated action of several players at the level of molecules, cells and tissues. In mammals, it is controlled by a specialized population of migratory extraembryonic epithelial cells, the anterior visceral endoderm (AVE). The AVE is a signalling centre that is responsible for several important patterning events during early development, including specifying the orientation of the A–P axis and the position of the heart with respect to the brain. AVE cells undergo a characteristic stereotypical migration which is crucial to their functions. The Royal Society 2014-12-05 /pmc/articles/PMC4216468/ /pubmed/25349454 http://dx.doi.org/10.1098/rstb.2013.0546 Text en http://creativecommons.org/licenses/by/3.0/ © 2014 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Articles
Stower, Matthew J.
Srinivas, Shankar
Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo
title Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo
title_full Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo
title_fullStr Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo
title_full_unstemmed Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo
title_short Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo
title_sort heading forwards: anterior visceral endoderm migration in patterning the mouse embryo
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216468/
https://www.ncbi.nlm.nih.gov/pubmed/25349454
http://dx.doi.org/10.1098/rstb.2013.0546
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