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A bone fide atypical fibroxanthoma of penis
Malignant mesenchymal tumors of the penis are very rare and they have vascular origin. We present a case of a 71-year-old man with a painless nodule of 2.0 cm in diameter located in the penile foreskin. There was no history of urinary or sexually transmitted disease. An excisional biopsy revealed a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216554/ https://www.ncbi.nlm.nih.gov/pubmed/25371625 http://dx.doi.org/10.4103/0974-7796.141009 |
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author | Cuomo, Roberto Addesso, Maria Altieri, Roberto D’Antonio, Antonio |
author_facet | Cuomo, Roberto Addesso, Maria Altieri, Roberto D’Antonio, Antonio |
author_sort | Cuomo, Roberto |
collection | PubMed |
description | Malignant mesenchymal tumors of the penis are very rare and they have vascular origin. We present a case of a 71-year-old man with a painless nodule of 2.0 cm in diameter located in the penile foreskin. There was no history of urinary or sexually transmitted disease. An excisional biopsy revealed a markedly pleomorphic sarcoma resembling atypical fibroxanthoma (AFX) associated with a squamous cell carcinoma in situ. The patient refused a wide re-excision and was free of disease after 36 months. Because the different therapeutic management and prognosis, differential diagnosis should be made with sarcomatoid squamous cell carcinoma and melanoma: A diagnosis of AFX or malignant fibrous histiocytoma may be considered only after the complete exclusion of these two entities. |
format | Online Article Text |
id | pubmed-4216554 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-42165542014-11-04 A bone fide atypical fibroxanthoma of penis Cuomo, Roberto Addesso, Maria Altieri, Roberto D’Antonio, Antonio Urol Ann Case Report Malignant mesenchymal tumors of the penis are very rare and they have vascular origin. We present a case of a 71-year-old man with a painless nodule of 2.0 cm in diameter located in the penile foreskin. There was no history of urinary or sexually transmitted disease. An excisional biopsy revealed a markedly pleomorphic sarcoma resembling atypical fibroxanthoma (AFX) associated with a squamous cell carcinoma in situ. The patient refused a wide re-excision and was free of disease after 36 months. Because the different therapeutic management and prognosis, differential diagnosis should be made with sarcomatoid squamous cell carcinoma and melanoma: A diagnosis of AFX or malignant fibrous histiocytoma may be considered only after the complete exclusion of these two entities. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4216554/ /pubmed/25371625 http://dx.doi.org/10.4103/0974-7796.141009 Text en Copyright: © Urology Annals http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Cuomo, Roberto Addesso, Maria Altieri, Roberto D’Antonio, Antonio A bone fide atypical fibroxanthoma of penis |
title | A bone fide atypical fibroxanthoma of penis |
title_full | A bone fide atypical fibroxanthoma of penis |
title_fullStr | A bone fide atypical fibroxanthoma of penis |
title_full_unstemmed | A bone fide atypical fibroxanthoma of penis |
title_short | A bone fide atypical fibroxanthoma of penis |
title_sort | bone fide atypical fibroxanthoma of penis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216554/ https://www.ncbi.nlm.nih.gov/pubmed/25371625 http://dx.doi.org/10.4103/0974-7796.141009 |
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