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A bone fide atypical fibroxanthoma of penis

Malignant mesenchymal tumors of the penis are very rare and they have vascular origin. We present a case of a 71-year-old man with a painless nodule of 2.0 cm in diameter located in the penile foreskin. There was no history of urinary or sexually transmitted disease. An excisional biopsy revealed a...

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Autores principales: Cuomo, Roberto, Addesso, Maria, Altieri, Roberto, D’Antonio, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216554/
https://www.ncbi.nlm.nih.gov/pubmed/25371625
http://dx.doi.org/10.4103/0974-7796.141009
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author Cuomo, Roberto
Addesso, Maria
Altieri, Roberto
D’Antonio, Antonio
author_facet Cuomo, Roberto
Addesso, Maria
Altieri, Roberto
D’Antonio, Antonio
author_sort Cuomo, Roberto
collection PubMed
description Malignant mesenchymal tumors of the penis are very rare and they have vascular origin. We present a case of a 71-year-old man with a painless nodule of 2.0 cm in diameter located in the penile foreskin. There was no history of urinary or sexually transmitted disease. An excisional biopsy revealed a markedly pleomorphic sarcoma resembling atypical fibroxanthoma (AFX) associated with a squamous cell carcinoma in situ. The patient refused a wide re-excision and was free of disease after 36 months. Because the different therapeutic management and prognosis, differential diagnosis should be made with sarcomatoid squamous cell carcinoma and melanoma: A diagnosis of AFX or malignant fibrous histiocytoma may be considered only after the complete exclusion of these two entities.
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spelling pubmed-42165542014-11-04 A bone fide atypical fibroxanthoma of penis Cuomo, Roberto Addesso, Maria Altieri, Roberto D’Antonio, Antonio Urol Ann Case Report Malignant mesenchymal tumors of the penis are very rare and they have vascular origin. We present a case of a 71-year-old man with a painless nodule of 2.0 cm in diameter located in the penile foreskin. There was no history of urinary or sexually transmitted disease. An excisional biopsy revealed a markedly pleomorphic sarcoma resembling atypical fibroxanthoma (AFX) associated with a squamous cell carcinoma in situ. The patient refused a wide re-excision and was free of disease after 36 months. Because the different therapeutic management and prognosis, differential diagnosis should be made with sarcomatoid squamous cell carcinoma and melanoma: A diagnosis of AFX or malignant fibrous histiocytoma may be considered only after the complete exclusion of these two entities. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4216554/ /pubmed/25371625 http://dx.doi.org/10.4103/0974-7796.141009 Text en Copyright: © Urology Annals http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cuomo, Roberto
Addesso, Maria
Altieri, Roberto
D’Antonio, Antonio
A bone fide atypical fibroxanthoma of penis
title A bone fide atypical fibroxanthoma of penis
title_full A bone fide atypical fibroxanthoma of penis
title_fullStr A bone fide atypical fibroxanthoma of penis
title_full_unstemmed A bone fide atypical fibroxanthoma of penis
title_short A bone fide atypical fibroxanthoma of penis
title_sort bone fide atypical fibroxanthoma of penis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216554/
https://www.ncbi.nlm.nih.gov/pubmed/25371625
http://dx.doi.org/10.4103/0974-7796.141009
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