Microcephaly Disease Gene Wdr62 Regulates Mitotic Progression of Embryonic Neural Stem Cells and Brain Size

Human genetic studies have established a link between a class of centrosome proteins and microcephaly. Current studies of microcephaly focus on defective centrosome/spindle orientation. Mutations in WDR62 are associated with microcephaly and other cortical abnormalities in humans. Here we create a m...

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Detalles Bibliográficos
Autores principales: Chen, Jian-Fu, Zhang, Ying, Wilde, Jonathan, Hansen, Kirk, Lai, Fan, Niswander, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216695/
https://www.ncbi.nlm.nih.gov/pubmed/24875059
http://dx.doi.org/10.1038/ncomms4885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216695/
https://www.ncbi.nlm.nih.gov/pubmed/24875059
http://dx.doi.org/10.1038/ncomms4885

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