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cMET Activation and EGFR-Directed Therapy Resistance in Triple-Negative Breast Cancer
Background: EGFR expression and pathway activation are common in triple-negative breast cancer (TNBC). However, anti-EGFR therapies have not been effective in these patients. We aimed to study the efficacy of targeting MET in overcoming resistance to EGFR therapy in TNBC cell lines. Methods: TNBC li...
Autores principales: | Sohn, Joohyuk, Liu, Shuying, Parinyanitikul, Napa, Lee, Jangsoon, Hortobagyi, Gabriel N., Mills, Gordon B., Ueno, Naoto T., Gonzalez-Angulo, Ana M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216798/ https://www.ncbi.nlm.nih.gov/pubmed/25368674 http://dx.doi.org/10.7150/jca.9696 |
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