Estimating genotype error rates from high-coverage next-generation sequence data

Exome and whole-genome sequencing studies are becoming increasingly common, but little is known about the accuracy of the genotype calls made by the commonly used platforms. Here we use replicate high-coverage sequencing of blood and saliva DNA samples from four European-American individuals to esti...

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Detalles Bibliográficos
Autores principales: Wall, Jeffrey D., Tang, Ling Fung, Zerbe, Brandon, Kvale, Mark N., Kwok, Pui-Yan, Schaefer, Catherine, Risch, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216915/
https://www.ncbi.nlm.nih.gov/pubmed/25304867
http://dx.doi.org/10.1101/gr.168393.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216915/
https://www.ncbi.nlm.nih.gov/pubmed/25304867
http://dx.doi.org/10.1101/gr.168393.113

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