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Application of histone modification-specific interaction domains as an alternative to antibodies

Post-translational modifications (PTMs) of histones constitute a major chromatin indexing mechanism, and their proper characterization is of highest biological importance. So far, PTM-specific antibodies have been the standard reagent for studying histone PTMs despite caveats such as lot-to-lot vari...

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Detalles Bibliográficos
Autores principales: Kungulovski, Goran, Kycia, Ina, Tamas, Raluca, Jurkowska, Renata Z., Kudithipudi, Srikanth, Henry, Chisato, Reinhardt, Richard, Labhart, Paul, Jeltsch, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216925/
https://www.ncbi.nlm.nih.gov/pubmed/25301795
http://dx.doi.org/10.1101/gr.170985.113