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Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C

Genome-wide association studies have identified more than 70 common variants that are associated with breast cancer risk. Most of these variants map to non-protein-coding regions and several map to gene deserts, regions of several hundred kilobases lacking protein-coding genes. We hypothesized that...

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Detalles Bibliográficos
Autores principales: Dryden, Nicola H., Broome, Laura R., Dudbridge, Frank, Johnson, Nichola, Orr, Nick, Schoenfelder, Stefan, Nagano, Takashi, Andrews, Simon, Wingett, Steven, Kozarewa, Iwanka, Assiotis, Ioannis, Fenwick, Kerry, Maguire, Sarah L., Campbell, James, Natrajan, Rachael, Lambros, Maryou, Perrakis, Eleni, Ashworth, Alan, Fraser, Peter, Fletcher, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216926/
https://www.ncbi.nlm.nih.gov/pubmed/25122612
http://dx.doi.org/10.1101/gr.175034.114