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TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids

Plasma membrane lipid composition must be maintained during growth and under environmental insult. In yeast, signaling mediated by TOR Complex 2 (TORC2)-dependent protein kinase Ypk1 controls lipid abundance and distribution in response to membrane stress. Ypk1, among other actions, alleviates negat...

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Detalles Bibliográficos
Autores principales:	Muir, Alexander, Ramachandran, Subramaniam, Roelants, Françoise M, Timmons, Garrett, Thorner, Jeremy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217029/ https://www.ncbi.nlm.nih.gov/pubmed/25279700 http://dx.doi.org/10.7554/eLife.03779

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