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The Varied Roles of Nuclear Argonaute-Small RNA Complexes and Avenues for Therapy

Argonautes are highly conserved proteins found in almost all eukaryotes and some bacteria and archaea. In humans, there are eight argonaute proteins evenly distributed across two clades, the Ago clade (AGO1-4) and the Piwi clade (PIWIL1-4). The function of Ago proteins is best characterized by their...

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Detalles Bibliográficos
Autores principales:	Ross, Jason P, Kassir, Zena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217078/ https://www.ncbi.nlm.nih.gov/pubmed/25313622 http://dx.doi.org/10.1038/mtna.2014.54

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