Evi1 defines leukemia-initiating capacity and tyrosine kinase inhibitor resistance in chronic myeloid leukemia

Relapse of chronic myeloid leukemia (CML) is triggered by stem cells with a reconstituting capacity similar to that of hematopoietic stem cells (HSCs) and CML stem cells are a source of resistance in drug therapy with tyrosine kinase inhibitors (TKIs). Ecotropic viral integration site 1 (EVI1), a ke...

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Detalles Bibliográficos
Autores principales: Sato, T, Goyama, S, Kataoka, K, Nasu, R, Tsuruta-Kishino, T, Kagoya, Y, Nukina, A, Kumagai, K, Kubota, N, Nakagawa, M, Arai, S, Yoshimi, A, Honda, H, Kadowaki, T, Kurokawa, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217142/
https://www.ncbi.nlm.nih.gov/pubmed/24747972
http://dx.doi.org/10.1038/onc.2014.108

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