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Targeted NGS: A Cost-Effective Approach to Molecular Diagnosis of PIDs

Background: Primary immunodeficiencies (PIDs) are a diverse group of disorders caused by multiple genetic defects. Obtaining a molecular diagnosis for PID patients using a phenotype-based approach is often complex, expensive, and not always successful. Next-generation sequencing (NGS) methods offer...

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Detalles Bibliográficos
Autores principales:	Stoddard, Jennifer L., Niemela, Julie E., Fleisher, Thomas A., Rosenzweig, Sergio D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217515/ https://www.ncbi.nlm.nih.gov/pubmed/25404929 http://dx.doi.org/10.3389/fimmu.2014.00531

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