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Genome-wide analysis of non-coding regulatory mutations in cancer

Cancer primarily develops due to somatic alterations in the genome. Advances in sequencing have enabled large-scale sequencing studies across many tumor types, emphasizing discovery of alterations in protein-coding genes. However, the protein-coding exome comprises less than 2% of the human genome....

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Detalles Bibliográficos
Autores principales:	Weinhold, Nils, Jacobsen, Anders, Schultz, Nikolaus, Sander, Chris, Lee, William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217527/ https://www.ncbi.nlm.nih.gov/pubmed/25261935 http://dx.doi.org/10.1038/ng.3101

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