Human pre-B cell receptor signal transduction: evidence for distinct roles of PI3kinase and MAP-kinase signalling pathways

Pre-BCR acts as a critical checkpoint in B cell development. However, its signalling cascade still remains indistinctly characterised in human. We investigated pre-BCR signalling pathway to examine its regulation in normal primary pre-B lymphocytes and pre-B cell lines. In cell lines, early signalli...

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Detalles Bibliográficos
Autores principales: Anbazhagan, Kolandaswamy, Rabbind Singh, Amrathlal, Isabelle, Piec, Stella, Ibata, Céline, Alleaume-De Martel, Bissac, Eliane, Bertrand, Brassart, Rémy, Nyga, Naomi, Taylor, Vincent, Fuentes, Rochette, Jacques, Lassoued, Kaïss
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217539/
https://www.ncbi.nlm.nih.gov/pubmed/25400915
http://dx.doi.org/10.1002/iid3.4

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