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Association between diabetes mellitus with metabolic syndrome and diabetic microangiopathy
The aim of this study was to investigate the association between diabetes mellitus (DM), mainly type II, with metabolic syndrome (MS) and diabetic nephropathy (DN)/diabetic retinopathy (DR). Based on the analysis of the prevalence of MS, patients with DM were divided into MS and non-MS groups accord...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217776/ https://www.ncbi.nlm.nih.gov/pubmed/25371746 http://dx.doi.org/10.3892/etm.2014.1992 |
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author | ZHANG, XIAOYAN CUI, XIAOLI LI, FENGHUA WANG, SHUO LIU, XINYU HUI, LICHAO SONG, NA LI, NANNAN |
author_facet | ZHANG, XIAOYAN CUI, XIAOLI LI, FENGHUA WANG, SHUO LIU, XINYU HUI, LICHAO SONG, NA LI, NANNAN |
author_sort | ZHANG, XIAOYAN |
collection | PubMed |
description | The aim of this study was to investigate the association between diabetes mellitus (DM), mainly type II, with metabolic syndrome (MS) and diabetic nephropathy (DN)/diabetic retinopathy (DR). Based on the analysis of the prevalence of MS, patients with DM were divided into MS and non-MS groups according to the presence or absence of MS. The correlation between DN, DR and certain factors, including gender, age, disease duration and the presence or absence of a family history of MS, were analyzed. The prevalence of MS among the patients with DM was 62.50%. The prevalence of DN was 55.33% in the MS group and that of DR was 26.00%. DN was positively correlated with age, gender, blood pressure, triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and blood uric acid. DR was positively correlated with traceable disease duration and LDL-C. In conclusion, DM occurred more frequently in concurrence with MS than without MS, and the prevalence of DN/DR in the MS group was higher than that in the non-MS group. Age, gender, blood pressure, TG, LDL-C and blood uric acid were risk factors for DN and the traceable disease duration and LDL-C were risk factors for DR. |
format | Online Article Text |
id | pubmed-4217776 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-42177762014-11-04 Association between diabetes mellitus with metabolic syndrome and diabetic microangiopathy ZHANG, XIAOYAN CUI, XIAOLI LI, FENGHUA WANG, SHUO LIU, XINYU HUI, LICHAO SONG, NA LI, NANNAN Exp Ther Med Articles The aim of this study was to investigate the association between diabetes mellitus (DM), mainly type II, with metabolic syndrome (MS) and diabetic nephropathy (DN)/diabetic retinopathy (DR). Based on the analysis of the prevalence of MS, patients with DM were divided into MS and non-MS groups according to the presence or absence of MS. The correlation between DN, DR and certain factors, including gender, age, disease duration and the presence or absence of a family history of MS, were analyzed. The prevalence of MS among the patients with DM was 62.50%. The prevalence of DN was 55.33% in the MS group and that of DR was 26.00%. DN was positively correlated with age, gender, blood pressure, triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and blood uric acid. DR was positively correlated with traceable disease duration and LDL-C. In conclusion, DM occurred more frequently in concurrence with MS than without MS, and the prevalence of DN/DR in the MS group was higher than that in the non-MS group. Age, gender, blood pressure, TG, LDL-C and blood uric acid were risk factors for DN and the traceable disease duration and LDL-C were risk factors for DR. D.A. Spandidos 2014-12 2014-09-29 /pmc/articles/PMC4217776/ /pubmed/25371746 http://dx.doi.org/10.3892/etm.2014.1992 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles ZHANG, XIAOYAN CUI, XIAOLI LI, FENGHUA WANG, SHUO LIU, XINYU HUI, LICHAO SONG, NA LI, NANNAN Association between diabetes mellitus with metabolic syndrome and diabetic microangiopathy |
title | Association between diabetes mellitus with metabolic syndrome and diabetic microangiopathy |
title_full | Association between diabetes mellitus with metabolic syndrome and diabetic microangiopathy |
title_fullStr | Association between diabetes mellitus with metabolic syndrome and diabetic microangiopathy |
title_full_unstemmed | Association between diabetes mellitus with metabolic syndrome and diabetic microangiopathy |
title_short | Association between diabetes mellitus with metabolic syndrome and diabetic microangiopathy |
title_sort | association between diabetes mellitus with metabolic syndrome and diabetic microangiopathy |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217776/ https://www.ncbi.nlm.nih.gov/pubmed/25371746 http://dx.doi.org/10.3892/etm.2014.1992 |
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