Protective effects of N-acetylcysteine on cisplatin-induced oxidative stress and DNA damage in HepG2 cells

Hepatocyte injury is a common pathological effect of cisplatin (CDDP) in various solid tumor therapies. Thus, strategies for minimizing CDDP toxicity are of great clinical interest. N-acetylcysteine (NAC), a known antioxidant, is often used as an antidote for acetaminophen overdose in the clinic due...

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Detalles Bibliográficos
Autores principales: WANG, FUGEN, LIU, SHOURONG, SHEN, YIQIN, ZHUANG, RANGXIAO, XI, JIANJUN, FANG, HONGYING, PAN, XUWAN, SUN, JINGJING, CAI, ZHAOBIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218661/
https://www.ncbi.nlm.nih.gov/pubmed/25371760
http://dx.doi.org/10.3892/etm.2014.2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218661/
https://www.ncbi.nlm.nih.gov/pubmed/25371760
http://dx.doi.org/10.3892/etm.2014.2019

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