Cargando…

Protective effects of N-acetylcysteine on cisplatin-induced oxidative stress and DNA damage in HepG2 cells

Hepatocyte injury is a common pathological effect of cisplatin (CDDP) in various solid tumor therapies. Thus, strategies for minimizing CDDP toxicity are of great clinical interest. N-acetylcysteine (NAC), a known antioxidant, is often used as an antidote for acetaminophen overdose in the clinic due...

Descripción completa

Detalles Bibliográficos
Autores principales:	WANG, FUGEN, LIU, SHOURONG, SHEN, YIQIN, ZHUANG, RANGXIAO, XI, JIANJUN, FANG, HONGYING, PAN, XUWAN, SUN, JINGJING, CAI, ZHAOBIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218661/ https://www.ncbi.nlm.nih.gov/pubmed/25371760 http://dx.doi.org/10.3892/etm.2014.2019

Ejemplares similares

Protective effect of apigenin magnesium complex on H(2)O(2)-induced oxidative stress and inflammatory responses in rat hepatic stellate cells
por: Pan, Xuwang, et al.
Publicado: (2020)

Protective effect of N-acetylcysteine activated carbon release microcapsule on myocardial ischemia-reperfusion injury in rats
por: Cai, Zhaobin, et al.
Publicado: (2018)

Activated carbon N-acetylcysteine microcapsule protects against nonalcoholic fatty liver disease in young rats via activating telomerase and inhibiting apoptosis
por: Shi, Tingting, et al.
Publicado: (2018)

Cisplatin-resistant HepG2 cell-derived exosomes transfer cisplatin resistance to cisplatin-sensitive cells in HCC
por: Tang, Zuxiong, et al.
Publicado: (2021)

VX680 suppresses the growth of HepG2 cells and enhances the chemosensitivity to cisplatin
por: YAO, RUCHENG, et al.
Publicado: (2014)

Effects of dihydroartemisinin combined with cisplatin on proliferation, apoptosis and migration of HepG2 cells
por: Rao, Qi, et al.
Publicado: (2022)

The Protective Effect of Trichosanthes kirilowii Peel Polysaccharide on the Oxidative Damaged HepG2 and HUASMC Cells
por: Zhang, Jinli, et al.
Publicado: (2022)

Evaluation of Cisplatin Efficacy on HepG2 and E. coli Cells under Acidic Conditions
por: Babaei, Faezeh, et al.
Publicado: (2019)

Lovastatin prevents bleomycin-induced DNA damage to HepG2 cells
por: Nasiri, Marjan, et al.
Publicado: (2016)

Effects of ginkgol C17:1 on cisplatin-induced autophagy and apoptosis in HepG2 cells
por: Liu, Jun, et al.
Publicado: (2018)

Ursolic acid sensitizes cisplatin-resistant HepG2/DDP cells to cisplatin via inhibiting Nrf2/ARE pathway
por: Wu, Shouhai, et al.
Publicado: (2016)

Protective effects of the extracts of Barringtonia racemosa shoots against oxidative damage in HepG2 cells
por: Kong, Kin Weng, et al.
Publicado: (2016)

Ferulic acid protects HepG2 cells and mouse liver from iron-induced damage
por: Kose, Tugba, et al.
Publicado: (2023)

Nanoceria Attenuated High Glucose-Induced Oxidative Damage in HepG2 Cells
por: Shokrzadeh, Mohammad, et al.
Publicado: (2016)

Effects of Sinapic Acid Combined with Cisplatin on the Apoptosis and Autophagy of the Hepatoma Cells HepG2 and SMMC-7721
por: Zhao, Jian, et al.
Publicado: (2021)

Elevated extracellular calcium ions accelerate the proliferation and migration of HepG2 cells and decrease cisplatin sensitivity
por: Xu, Haozhe, et al.
Publicado: (2023)

Artificial cells eavesdropping on HepG2 cells
por: Westensee, Isabella Nymann, et al.
Publicado: (2023)

Pyrroloquinoline quinone alleviates oxidative damage induced by high glucose in HepG2 cells
por: Alkahtani, Saad, et al.
Publicado: (2021)

Antialcohol and Hepatoprotective Effects of Tamarind Shell Extract on Ethanol-Induced Damage to HepG2 Cells and Animal Models
por: Han, Shao-Cong, et al.
Publicado: (2023)

Effects of activated carbon N-acetylcysteine sustained-release microcapsule on dipeptidyl peptidase IV expression in young rats with non-alcoholic fatty liver disease
por: Zhou, Hongping, et al.
Publicado: (2017)

Anti-tumor effect of volatile oil from Houttuynia cordata Thunb. on HepG2 cells and HepG2 tumor-bearing mice
por: Yang, Linsong, et al.
Publicado: (2019)

DNMT1/PKR double knockdowned HepG2 (HepG2-DP) cells have high hepatic function and differentiation ability
por: Tanaka-yachi, Rieko, et al.
Publicado: (2022)

Matrix Metalloproteinase 2 Knockdown Suppresses the Proliferation of HepG2 and Huh7 Cells and Enhances the Cisplatin Effect
por: Liu, Jiangwei, et al.
Publicado: (2019)

Protective effects of exosomes derived from lyophilized porcine liver against acetaminophen damage on HepG2 cells
por: Tassinari, Riccardo, et al.
Publicado: (2021)

Preparation of antioxidant peptides from Moringa oleifera leaves and their protection against oxidative damage in HepG2 cells
por: Tao, Liang, et al.
Publicado: (2022)

Characterization of dengue virus entry into HepG2 cells
por: Suksanpaisan, Lukkana, et al.
Publicado: (2009)

Selectivity of biopolymer membranes using HepG2 cells
por: Lü, Dongyuan, et al.
Publicado: (2015)

Curcumin Effect on Copper Transport in HepG2 Cells
por: Berzina, Anita, et al.
Publicado: (2018)

Cholesterol-lowing effect of taurine in HepG2 cell
por: Guo, Junxia, et al.
Publicado: (2017)

Nevirapine induced mitochondrial dysfunction in HepG2 cells
por: Paemanee, Atchara, et al.
Publicado: (2017)

The Expectation and Reality of the HepG2 Core Metabolic Profile
por: Kiseleva, Olga I., et al.
Publicado: (2023)

Embelin-induced apoptosis of HepG2 human hepatocellular carcinoma cells and blockade of HepG2 cells in the G2/M phase via the mitochondrial pathway
por: TAGHIYEV, ASAF, et al.
Publicado: (2012)

Mitochondrial ROS contribute to oridonin-induced HepG2 apoptosis through PARP activation
por: Liu, Xiaoning, et al.
Publicado: (2018)

Arsenic trioxide reduces chemo-resistance to 5-fluorouracil and cisplatin in HBx-HepG2 cells via complex mechanisms
por: Yu, Guifang, et al.
Publicado: (2015)

In Vitro Protective Effect of Paste and Sauce Extract Made with Protaetia brevitarsis Larvae on HepG2 Cells Damaged by Ethanol
por: Hwang, Dooseon, et al.
Publicado: (2020)

Ginkgo biloba L. Leaf Extract Protects HepG2 Cells Against Paraquat-Induced Oxidative DNA Damage
por: Silva, Amélia M., et al.
Publicado: (2019)

Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen
por: Lai, Alvina G., et al.
Publicado: (2018)

TMEM2 inhibits hepatitis B virus infection in HepG2 and HepG2.2.15 cells by activating the JAK–STAT signaling pathway
por: Zhu, X, et al.
Publicado: (2016)

Chinese liquor extract attenuates oxidative damage in HepG2 cells and extends lifespan of Caenorhabditis elegans
por: Liu, Jie, et al.
Publicado: (2020)

AngII induces HepG2 cells to activate epithelial-mesenchymal transition
por: Qi, Minghua, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3gpc44p2n55e5morocprl3gpgs