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Altered Protease–Activated Receptor-1 Expression and Signaling in a Malignant Pleural Mesothelioma Cell Line, NCI-H28, with Homozygous Deletion of the β-Catenin Gene

Protease activated receptors (PARs) are G-protein coupled receptors that are activated by an unique proteolytic mechanism. These receptors play crucial roles in hemostasis and thrombosis but also in inflammation and vascular development. PARs have also been implicated in tumor progression, invasion...

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Detalles Bibliográficos
Autores principales: Fazzini, Alessandra, D’Antongiovanni, Vanessa, Giusti, Laura, Da Valle, Ylenia, Ciregia, Federica, Piano, Ilaria, Caputo, Antonella, D’Ursi, Anna Maria, Gargini, Claudia, Lucacchini, Antonio, Mazzoni, Maria Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218765/
https://www.ncbi.nlm.nih.gov/pubmed/25364818
http://dx.doi.org/10.1371/journal.pone.0111550