Patient-Based Transcriptome-Wide Analysis Identify Interferon and Ubiquination Pathways as Potential Predictors of Influenza A Disease Severity

BACKGROUND: The influenza A virus is an RNA virus that is responsible for seasonal epidemics worldwide with up to five million cases of severe illness and 500,000 deaths annually according to the World Health Organization estimates. The factors associated with severe diseases are not well defined, b...

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Detalles Bibliográficos
Autores principales: Hoang, Long Truong, Tolfvenstam, Thomas, Ooi, Eng Eong, Khor, Chiea Chuen, Naim, Ahmand Nazri Mohamed, Ho, Eliza Xin Pei, Ong, Swee Hoe, Wertheim, Heiman F., Fox, Annette, Van Vinh Nguyen, Chau, Nghiem, Ngoc My, Ha, Tuan Manh, Thi Ngoc Tran, Anh, Tambayah, Paul, Lin, Raymond, Sangsajja, Chariya, Manosuthi, Weerawat, Chuchottaworn, Chareon, Sansayunh, Piamlarp, Chotpitayasunondh, Tawee, Suntarattiwong, Piyarat, Chokephaibulkit, Kulkanya, Puthavathana, Pilaipan, de Jong, Menno D., Farrar, Jeremy, van Doorn, H. Rogier, Hibberd, Martin Lloyd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218794/
https://www.ncbi.nlm.nih.gov/pubmed/25365328
http://dx.doi.org/10.1371/journal.pone.0111640

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