Analysis of FoxP3+ T-Regulatory Cells and CD8+T-Cells in Ovarian Carcinoma: Location and Tumor Infiltration Patterns Are Key Prognostic Markers

PURPOSE: Tumor infiltrating CD4+CD25+FoxP3+ regulatory immune cells (Treg) have been associated with impaired anti- tumor immune response and unfavorable prognosis for patients affected by ovarian carcinoma, whereas CD8+ T-cells have been found to positively influence survival rates in a large panel...

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Detalles Bibliográficos
Autores principales: Hermans, Cecilia, Anz, David, Engel, Jutta, Kirchner, Thomas, Endres, Stefan, Mayr, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218808/
https://www.ncbi.nlm.nih.gov/pubmed/25365237
http://dx.doi.org/10.1371/journal.pone.0111757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218808/
https://www.ncbi.nlm.nih.gov/pubmed/25365237
http://dx.doi.org/10.1371/journal.pone.0111757

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