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Analysis of FoxP3+ T-Regulatory Cells and CD8+T-Cells in Ovarian Carcinoma: Location and Tumor Infiltration Patterns Are Key Prognostic Markers
PURPOSE: Tumor infiltrating CD4+CD25+FoxP3+ regulatory immune cells (Treg) have been associated with impaired anti- tumor immune response and unfavorable prognosis for patients affected by ovarian carcinoma, whereas CD8+ T-cells have been found to positively influence survival rates in a large panel...
Autores principales: | Hermans, Cecilia, Anz, David, Engel, Jutta, Kirchner, Thomas, Endres, Stefan, Mayr, Doris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218808/ https://www.ncbi.nlm.nih.gov/pubmed/25365237 http://dx.doi.org/10.1371/journal.pone.0111757 |
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