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Fibroblast Growth Factor 21 Improves Insulin Sensitivity and Synergizes with Insulin in Human Adipose Stem Cell-Derived (hASC) Adipocytes

Fibroblast growth factor 21 (FGF21) has evolved as a major metabolic regulator, the pharmacological administration of which causes weight loss, insulin sensitivity and glucose control in rodents and humans. To understand the molecular mechanisms by which FGF21 exerts its metabolic effects, we develo...

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Detalles Bibliográficos
Autores principales: Lee, Darwin V., Li, Dongmei, Yan, Qingyun, Zhu, Yimin, Goodwin, Bryan, Calle, Roberto, Brenner, Martin B., Talukdar, Saswata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218812/
https://www.ncbi.nlm.nih.gov/pubmed/25365322
http://dx.doi.org/10.1371/journal.pone.0111767