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Fibroblast Growth Factor 21 Improves Insulin Sensitivity and Synergizes with Insulin in Human Adipose Stem Cell-Derived (hASC) Adipocytes
Fibroblast growth factor 21 (FGF21) has evolved as a major metabolic regulator, the pharmacological administration of which causes weight loss, insulin sensitivity and glucose control in rodents and humans. To understand the molecular mechanisms by which FGF21 exerts its metabolic effects, we develo...
Autores principales: | Lee, Darwin V., Li, Dongmei, Yan, Qingyun, Zhu, Yimin, Goodwin, Bryan, Calle, Roberto, Brenner, Martin B., Talukdar, Saswata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218812/ https://www.ncbi.nlm.nih.gov/pubmed/25365322 http://dx.doi.org/10.1371/journal.pone.0111767 |
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