Cargando…

High-Throughput Sequencing of Human Immunoglobulin Variable Regions with Subtype Identification

The humoral immune response plays a critical role in controlling infection, and the rapid adaptation to a broad range of pathogens depends on a highly diverse antibody repertoire. The advent of high-throughput sequencing technologies in the past decade has enabled insights into this immense diversit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schanz, Merle, Liechti, Thomas, Zagordi, Osvaldo, Miho, Enkelejda, Reddy, Sai T., Günthard, Huldrych F., Trkola, Alexandra, Huber, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218849/ https://www.ncbi.nlm.nih.gov/pubmed/25364977 http://dx.doi.org/10.1371/journal.pone.0111726

Ejemplares similares

OMIP‐047: High‐Dimensional phenotypic characterization of B cells
por: Liechti, Thomas, et al.
Publicado: (2018)

Cell-Cell Transmission Enables HIV-1 to Evade Inhibition by Potent CD4bs Directed Antibodies
por: Abela, Irene A., et al.
Publicado: (2012)

Broadly neutralizing antibodies: What is needed to move from a rare event in HIV-1 infection to vaccine efficacy?
por: Subbaraman, Harini, et al.
Publicado: (2018)

Widespread B cell perturbations in HIV-1 infection afflict naive and marginal zone B cells
por: Liechti, Thomas, et al.
Publicado: (2019)

Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality
por: Beauparlant, David, et al.
Publicado: (2017)

HIV-1 Subtype C, Tenofovir, and the Relationship With Treatment Failure and Drug Resistance
por: Günthard, Huldrych F., et al.
Publicado: (2016)

Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center
por: Scheier, Thomas, et al.
Publicado: (2021)

Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters
por: Brandenberg, Oliver F., et al.
Publicado: (2017)

Correction to: Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples
por: Lewandowska, Dagmara W., et al.
Publicado: (2017)

Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples
por: Lewandowska, Dagmara W., et al.
Publicado: (2017)

Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity
por: Kadelka, Claus, et al.
Publicado: (2018)

Complement Lysis Activity in Autologous Plasma Is Associated with Lower Viral Loads during the Acute Phase of HIV-1 Infection
por: Huber, Michael, et al.
Publicado: (2006)

Next-Generation Sequencing of HIV-1 RNA Genomes: Determination of Error Rates and Minimizing Artificial Recombination
por: Di Giallonardo, Francesca, et al.
Publicado: (2013)

Capacity of Broadly Neutralizing Antibodies to Inhibit HIV-1 Cell-Cell Transmission Is Strain- and Epitope-Dependent
por: Reh, Lucia, et al.
Publicado: (2015)

Two Years of Viral Metagenomics in a Tertiary Diagnostics Unit: Evaluation of the First 105 Cases
por: Kufner, Verena, et al.
Publicado: (2019)

Large-scale network analysis reveals the sequence space architecture of antibody repertoires
por: Miho, Enkelejda, et al.
Publicado: (2019)

HIV-1 replication activates CD4(+) T cells with specificities for persistent herpes viruses
por: Haas, Anna, et al.
Publicado: (2010)

Partial rescue of V1V2 mutant infectivity by HIV-1 cell-cell transmission supports the domain’s exceptional capacity for sequence variation
por: Brandenberg, Oliver F, et al.
Publicado: (2014)

Reply to correspondence ‘Conserved signatures indicate HIV-1 transmission is under strong selection and thus is not a “stochastic” process’ by Gonzalez et al., Retrovirology 2017
por: Oberle, Corinna S., et al.
Publicado: (2017)

Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies
por: Rusert, Peter, et al.
Publicado: (2011)

Unbiased metagenomic sequencing complements specific routine diagnostic methods and increases chances to detect rare viral strains
por: Lewandowska, Dagmara W., et al.
Publicado: (2015)

Assessing immunogenicity barriers of the HIV-1 envelope trimer
por: Maliqi, Liridona, et al.
Publicado: (2023)

Clustering and longitudinal change in SARS-CoV-2 seroprevalence in school children in the canton of Zurich, Switzerland: prospective cohort study of 55 schools
por: Ulyte, Agne, et al.
Publicado: (2021)

Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires
por: Miho, Enkelejda, et al.
Publicado: (2018)

Tailored enrichment strategy detects low abundant small noncoding RNAs in HIV-1 infected cells
por: Althaus, Claudia F, et al.
Publicado: (2012)

Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus C
por: Posada-Céspedes, Susana, et al.
Publicado: (2021)

High Efficacy of Saliva in Detecting SARS-CoV-2 by RT-PCR in Adults and Children
por: Huber, Michael, et al.
Publicado: (2021)

Reduced Relative Sensitivity of the Elecsys SARS-CoV-2 Antigen Assay in Saliva Compared to Nasopharyngeal Swabs
por: Audigé, Annette, et al.
Publicado: (2021)

Persistent mammalian orthoreovirus, coxsackievirus and adenovirus co-infection in a child with a primary immunodeficiency detected by metagenomic sequencing: a case report
por: Lewandowska, Dagmara W., et al.
Publicado: (2018)

Metagenomic sequencing complements routine diagnostics in identifying viral pathogens in lung transplant recipients with unknown etiology of respiratory infection
por: Lewandowska, Dagmara W., et al.
Publicado: (2017)

MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1
por: Ruprecht, Claudia R., et al.
Publicado: (2011)

Seroprofiling of Antibodies Against Endemic Human Coronaviruses and Severe Acute Respiratory Syndrome Coronavirus 2 in a Human Immunodeficiency Virus Cohort in Lesotho: Correlates of Antibody Response and Seropositivity
por: Brown, Jennifer A, et al.
Publicado: (2023)

Editorial Commentary: The Irreversibility of HIV Drug Resistance
por: Kouyos, Roger D., et al.
Publicado: (2015)

Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age
por: Ghraichy, Marie, et al.
Publicado: (2020)

Hepatitis C virus (HCV) genotype 1b displays higher genetic variability of hypervariable region 1 (HVR1) than genotype 3
por: Janiak, Maciej, et al.
Publicado: (2019)

A Novel High Throughput, Parallel Infection Assay for Determining the Replication Capacities of 346 Primary HIV-1 Isolates of the Zurich Primary HIV-1 Infection Study in Primary Cells
por: Rindler, Audrey E., et al.
Publicado: (2021)

A deletion map of the human immunoglobulin heavy chain variable region
Publicado: (1991)

A new variable region in mouse immunoglobulin lambda light chains
Publicado: (1987)

Activation and Tolerance in CD4(+) T Cells Reactive to an Immunoglobulin Variable Region
por: Snyder, Christopher M., et al.
Publicado: (2004)

Organization of the variable region of the immunoglobulin heavy-chain gene locus of the rat
por: Hendricks, Jacobus, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_nis8guo3eku68ciog0bm28dp5l