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Defining the Alloreactive T Cell Repertoire Using High-Throughput Sequencing of Mixed Lymphocyte Reaction Culture

The cellular immune response is the most important mediator of allograft rejection and is a major barrier to transplant tolerance. Delineation of the depth and breadth of the alloreactive T cell repertoire and subsequent application of the technology to the clinic may improve patient outcomes. As a...

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Detalles Bibliográficos
Autores principales:	Emerson, Ryan O., Mathew, James M., Konieczna, Iwona M., Robins, Harlan S., Leventhal, Joseph R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218856/ https://www.ncbi.nlm.nih.gov/pubmed/25365040 http://dx.doi.org/10.1371/journal.pone.0111943

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